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The Glutamate Dehydrogenase Pathway and Its Roles in Cell and Tissue Biology in Health and Disease

Glutamate dehydrogenase (GDH) is a hexameric enzyme that catalyzes the reversible conversion of glutamate to α-ketoglutarate and ammonia while reducing NAD(P)(+) to NAD(P)H. It is found in all living organisms serving both catabolic and anabolic reactions. In mammalian tissues, oxidative deamination...

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Detalles Bibliográficos
Autores principales: Plaitakis, Andreas, Kalef-Ezra, Ester, Kotzamani, Dimitra, Zaganas, Ioannis, Spanaki, Cleanthe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372004/
https://www.ncbi.nlm.nih.gov/pubmed/28208702
http://dx.doi.org/10.3390/biology6010011