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SNP Discovery Using a Pangenome: Has the Single Reference Approach Become Obsolete?
Increasing evidence suggests that a single individual is insufficient to capture the genetic diversity within a species due to gene presence absence variation. In order to understand the extent to which genomic variation occurs in a species, the construction of its pangenome is necessary. The pangen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372014/ https://www.ncbi.nlm.nih.gov/pubmed/28287462 http://dx.doi.org/10.3390/biology6010021 |