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SNP Discovery Using a Pangenome: Has the Single Reference Approach Become Obsolete?

Increasing evidence suggests that a single individual is insufficient to capture the genetic diversity within a species due to gene presence absence variation. In order to understand the extent to which genomic variation occurs in a species, the construction of its pangenome is necessary. The pangen...

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Detalles Bibliográficos
Autores principales: Hurgobin, Bhavna, Edwards, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372014/
https://www.ncbi.nlm.nih.gov/pubmed/28287462
http://dx.doi.org/10.3390/biology6010021