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Impact of maternal antibodies and infant gut microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants: protocol for a prospective cohort study

INTRODUCTION: Gastroenteritis is the leading cause of morbidity and mortality among young children living in resource-poor settings, majority of which is attributed to rotavirus. Rotavirus vaccination can therefore have a significant impact on infant mortality. However, rotavirus vaccine efficacy in...

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Detalles Bibliográficos
Autores principales: Sindhu, Kuladaipalayam Natarajan C, Cunliffe, Nigel, Peak, Matthew, Turner, Mark, Darby, Alistair, Grassly, Nicholas, Gordon, Melita, Dube, Queen, Babji, Sudhir, Praharaj, Ira, Verghese, Valsan, Iturriza-Gómara, Miren, Kang, Gagandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372070/
https://www.ncbi.nlm.nih.gov/pubmed/28360258
http://dx.doi.org/10.1136/bmjopen-2017-016577