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Antibody-dependent-cellular-cytotoxicity-inducing antibodies significantly affect the post-exposure treatment of Ebola virus infection

Passive immunotherapy with monoclonal antibodies (mAbs) is an efficacious treatment for Ebola virus (EBOV) infections in animal models and humans. Understanding what constitutes a protective response is critical for the development of novel therapeutic strategies. We generated an EBOV-glycoprotein-p...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Fan, Changfa, Li, Qianqian, Zhou, Shuya, Huang, Weijin, Wang, Lan, Sun, Chunyun, Wang, Meng, Wu, Xi, Ma, Jian, Li, Baowen, Xie, Liangzhi, Wang, Youchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372081/
https://www.ncbi.nlm.nih.gov/pubmed/28358050
http://dx.doi.org/10.1038/srep45552