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HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis

HLA-B*15:02 screening before carbamazepine (CBZ) prescription in Asian populations is the recommended practice to prevent CBZ-induced Stevens-Johnson syndrome (CBZ-SJS). However, a number of patients have developed CBZ-SJS even having no HLA-B*15:02. Herein, we present the case of a Thai patient who...

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Detalles Bibliográficos
Autores principales: Jaruthamsophon, Kanoot, Tipmanee, Varomyalin, Sangiemchoey, Antida, Sukasem, Chonlaphat, Limprasert, Pornprot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372085/
https://www.ncbi.nlm.nih.gov/pubmed/28358139
http://dx.doi.org/10.1038/srep45553