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Synthesis and biological evaluation of novel ursolic acid analogues as potential α-glucosidase inhibitors

Ursolic acid (UA) is a major pentacyclic triterpenoid in plants, vegetables and fruits, which has been reported to have a potential anti-diabetic activity. Despite various semi-synthetic ursolic acid derivatives already described, new derivatives still need to be designed and synthesized to further...

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Detalles Bibliográficos
Autores principales: Wu, Pan-Pan, Zhang, Bing-Jie, Cui, Xi-Ping, Yang, Yang, Jiang, Zheng-Yun, Zhou, Zhi-Hong, Zhong, Ying-Ying, Mai, Yu-Ying, Ouyang, Zhong, Chen, Hui-Sheng, Zheng, Jie, Zhao, Su-Qing, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372089/
https://www.ncbi.nlm.nih.gov/pubmed/28358057
http://dx.doi.org/10.1038/srep45578