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Randomised controlled trial comparing ofatumumab to rituximab in children with steroid-dependent and calcineurin inhibitor-dependent idiopathic nephrotic syndrome: study protocol

INTRODUCTION: Oral steroids induce remission in about 90% of children with idiopathic nephrotic syndrome (INS), which is characterised by severe proteinuria and hypoalbuminaemia. Some children become steroid-dependent (SD) and require addition of calcineurin inhibitors (CNI) to maintain remission. S...

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Detalles Bibliográficos
Autores principales: Ravani, Pietro, Bonanni, Alice, Ghiggeri, Gian Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372102/
https://www.ncbi.nlm.nih.gov/pubmed/28314744
http://dx.doi.org/10.1136/bmjopen-2016-013319