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Deterministic encapsulation of single cells in thin tunable microgels for niche modeling and therapeutic delivery

Existing techniques to encapsulate cells into microscale hydrogels generally yield high polymer-to-cell ratios and lack control over the hydrogel’s mechanical properties(1). Here, we report a microfluidic-based method for encapsulating single cells in a ~6 micron layer of alginate that increases the...

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Detalles Bibliográficos
Autores principales: Mao, Angelo S., Shin, Jae-Won, Utech, Stefanie, Wang, Huanan, Uzun, Oktay, Li, Weiwei, Cooper, Madeline, Hu, Yuebi, Zhang, Liyuan, Weitz, David A., Mooney, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372217/
https://www.ncbi.nlm.nih.gov/pubmed/27798621
http://dx.doi.org/10.1038/nmat4781