Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation

Activation of synovial fibroblasts (SF) contributes to rheumatoid arthritis (RA) by damaging synovial membranes and generating inflammatory cytokines that recruit immune cells to the joint. In this paper we profile cytokine secretion by primary human SF from normal and RA donors and show that SF act...

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Detalles Bibliográficos
Autores principales: Jones, Douglas S., Jenney, Annie P., Swantek, Jennifer L., Burke, John M., Lauffenburger, Douglas A., Sorger, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372219/
https://www.ncbi.nlm.nih.gov/pubmed/27820799
http://dx.doi.org/10.1038/nchembio.2211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372219/
https://www.ncbi.nlm.nih.gov/pubmed/27820799
http://dx.doi.org/10.1038/nchembio.2211

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