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Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation
Activation of synovial fibroblasts (SF) contributes to rheumatoid arthritis (RA) by damaging synovial membranes and generating inflammatory cytokines that recruit immune cells to the joint. In this paper we profile cytokine secretion by primary human SF from normal and RA donors and show that SF act...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372219/ https://www.ncbi.nlm.nih.gov/pubmed/27820799 http://dx.doi.org/10.1038/nchembio.2211 |