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Understanding cell signaling in cancer stem cells for targeted therapy – can phosphoproteomics help to reveal the secrets?

BACKGROUND: Cancer represents heterogeneous and aberrantly proliferative manifestations composed of (epi)genetically and phenotypically distinct cells with a common clonal origin. Cancer stem cells (CSC) make up a rare subpopulation with the remarkable capacity to initiate, propagate and spread a ma...

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Detalles Bibliográficos
Autores principales: Gruber, Wolfgang, Scheidt, Tamara, Aberger, Fritz, Huber, Christian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372284/
https://www.ncbi.nlm.nih.gov/pubmed/28356110
http://dx.doi.org/10.1186/s12964-017-0166-1