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Excessive activation of the TLR9/TGF-β1/PDGF-B pathway in the peripheral blood of patients with systemic lupus erythematosus

BACKGROUND: Our aim is to study the existence of the TLR9/TGF-β1/PDGF-B pathway in healthy humans and patients with systemic lupus erythematosus (SLE), and to explore its possible involvement in the pathogenesis of lupus nephritis (LN). METHODS: Protein levels of the cytokines were detected by ELISA...

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Detalles Bibliográficos
Autores principales: Yuan, Yi, Yang, Mingyue, Wang, Kuo, Sun, Jing, Song, Lili, Diao, Xue, Jiang, Zhenyu, Cheng, Genhong, Wang, Xiaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372299/
https://www.ncbi.nlm.nih.gov/pubmed/28356164
http://dx.doi.org/10.1186/s13075-017-1238-8