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Dexmedetomidine’s inhibitory effects on acetylcholine release from cholinergic nerves in guinea pig trachea: a mechanism that accounts for its clinical benefit during airway irritation

BACKGROUND: Airway instrumentation can evoke upper airway reflexes including bronchoconstriction and cough which can cause serious complications including airway trauma, laryngospasm or bronchospasm which may in turn lead to difficulty with ventilation and hypoxemia. These airway events are mediated...

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Detalles Bibliográficos
Autores principales: Mikami, Maya, Zhang, Yi, Kim, Benjamin, Worgall, Tilla S., Groeben, Harald, Emala, Charles W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372301/
https://www.ncbi.nlm.nih.gov/pubmed/28356076
http://dx.doi.org/10.1186/s12871-017-0345-z