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Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7Rα antibodies in NOD mice
BACKGROUND: Type 1 diabetes is an autoimmune disease caused by T cell-mediated destruction of the insulin-producing β-cells in the pancreas. Therefore, approaches that effectively halt the pathogenic T cell response are predicted to have preventive or therapeutic benefit for type 1 diabetes patients...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372316/ https://www.ncbi.nlm.nih.gov/pubmed/28356069 http://dx.doi.org/10.1186/s12865-017-0201-4 |