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Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7Rα antibodies in NOD mice

BACKGROUND: Type 1 diabetes is an autoimmune disease caused by T cell-mediated destruction of the insulin-producing β-cells in the pancreas. Therefore, approaches that effectively halt the pathogenic T cell response are predicted to have preventive or therapeutic benefit for type 1 diabetes patients...

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Detalles Bibliográficos
Autores principales: Vazquez-Mateo, Cristina, Collins, Justin, Fleury, Michelle, Dooms, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372316/
https://www.ncbi.nlm.nih.gov/pubmed/28356069
http://dx.doi.org/10.1186/s12865-017-0201-4