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Tumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3β/β-catenin pathways

BACKGROUND: Metastasis is a major cause of death in human colorectal cancer patients. However, the contribution of chemokines in the tumor microenvironment to tumor metastasis is not fully understood. METHODS: Herein, we examinined several chemokines in colorectal cancer patients using chemokine ELI...

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Detalles Bibliográficos
Autores principales: Zhao, Jingkun, Ou, Baochi, Han, Dingpei, Wang, Puxiongzhi, Zong, Yaping, Zhu, Congcong, Liu, Di, Zheng, Minhua, Sun, Jing, Feng, Hao, Lu, Aiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372323/
https://www.ncbi.nlm.nih.gov/pubmed/28356111
http://dx.doi.org/10.1186/s12943-017-0629-4