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Down-regulation of E-cadherin enhances prostate cancer chemoresistance via Notch signaling

BACKGROUND: The chemoresistance of prostate cancer (PCa) is invariably associated with the aggressiveness and metastasis of this disease. New emerging evidence indicates that the epithelial-to-mesenchymal transition (EMT) may play pivotal roles in the development of chemoresistance and metastasis. A...

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Detalles Bibliográficos
Autores principales: Wang, Wenchu, Wang, Lihui, Mizokami, Atsushi, Shi, Junlin, Zou, Chunlin, Dai, Jinlu, Keller, Evan T., Lu, Yi, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372329/
https://www.ncbi.nlm.nih.gov/pubmed/28356132
http://dx.doi.org/10.1186/s40880-017-0203-x