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Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo

BACKGROUND: Astrocyte activation is a hallmark of traumatic brain injury resulting in neurological dysfunction or death for an overproduction of inflammatory cytokines and glial scar formation. Both the silent mating type information (Sirt1) expression and mitogen-activated protein kinase (MAPK) sig...

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Detalles Bibliográficos
Autores principales:	Li, Dan, Liu, Nan, Zhao, Hai-Hua, Zhang, Xu, Kawano, Hitoshi, Liu, Lu, Zhao, Liang, Li, Hong-Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372348/ https://www.ncbi.nlm.nih.gov/pubmed/28356158 http://dx.doi.org/10.1186/s12974-017-0841-6

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