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Downregulation of LIMK1–ADF/cofilin by DADS inhibits the migration and invasion of colon cancer

This study aimed to explore whether the downregulation of LIM kinase 1 (LIMK1)-actin depolymerization factor (ADF, also known as destrin)/cofilin by diallyl disulfide (DADS) inhibited the migration and invasion of colon cancer. Previous studies have shown that silencing LIMK1 could significantly enh...

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Detalles Bibliográficos
Autores principales: Su, Jian, Zhou, Yujuan, Pan, Zhibing, Shi, Ling, Yang, Jing, Liao, Aijun, Liao, Qianjin, Su, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372356/
https://www.ncbi.nlm.nih.gov/pubmed/28358024
http://dx.doi.org/10.1038/srep45624