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Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment

A new group of compounds, promising for the design of original multitarget therapeutic agents for treating neurodegenerative diseases, based on conjugates of aminoadamantane and carbazole derivatives was synthesized and investigated. Compounds of these series were found to interact with a group of t...

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Detalles Bibliográficos
Autores principales: Bachurin, Sergey O., Shevtsova, Elena F., Makhaeva, Galina F., Grigoriev, Vladimir V., Boltneva, Natalia P., Kovaleva, Nadezhda V., Lushchekina, Sofya V., Shevtsov, Pavel N., Neganova, Margarita E., Redkozubova, Olga M., Bovina, Elena V., Gabrelyan, Alexey V., Fisenko, Vladimir P., Sokolov, Vladimir B., Aksinenko, Alexey Yu, Echeverria, Valentina, Barreto, George E., Aliev, Gjumrakch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372361/
https://www.ncbi.nlm.nih.gov/pubmed/28358144
http://dx.doi.org/10.1038/srep45627