Mechanistic prediction of food effects for Compound A tablet using PBPK model

Physiologically based pharmacokinetic (PBPK) modeling has been extensively used to study the factors of effect drug absorption, distribution, metabolize and extraction progress in human. In this study, Compound A(CPD A) is a BCS Class II drug, which has been extensive applied in clinical as lipid-lo...

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Detalles Bibliográficos
Autores principales: Li, Xueqing, Shi, Lei, Tang, Xiuling, Wang, Qinghui, Zhou, Lun, Song, Wei, Feng, Zhijun, Ge, Jie, Li, Jian Kang, Yang, Lin, Wen, Aidong, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372427/
https://www.ncbi.nlm.nih.gov/pubmed/28386186
http://dx.doi.org/10.1016/j.sjbs.2017.01.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372427/
https://www.ncbi.nlm.nih.gov/pubmed/28386186
http://dx.doi.org/10.1016/j.sjbs.2017.01.032

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