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High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors

An increasing number of neurodegenerative diseases are being found to be associated with the abnormal accumulation of aggregated proteins in the brain. In Parkinson’s disease, this process involves the aggregation of alpha-synuclein (α-syn) into intraneuronal inclusions. Thus, compounds that inhibit...

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Detalles Bibliográficos
Autores principales: Pujols, Jordi, Peña-Díaz, Samuel, Conde-Giménez, María, Pinheiro, Francisca, Navarro, Susanna, Sancho, Javier, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372494/
https://www.ncbi.nlm.nih.gov/pubmed/28257086
http://dx.doi.org/10.3390/ijms18030478