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Hotspot Selective Preference of the Chimeric Sequences Formed in Multiple Displacement Amplification
Multiple displacement amplification (MDA) is considered to be a conventional approach to comprehensive amplification from low input DNA. The chimeric reads generated in MDA lead to severe disruption in some studies, including those focusing on heterogeneity, structural variation, and genetic recombi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372508/ https://www.ncbi.nlm.nih.gov/pubmed/28245591 http://dx.doi.org/10.3390/ijms18030492 |