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Hotspot Selective Preference of the Chimeric Sequences Formed in Multiple Displacement Amplification

Multiple displacement amplification (MDA) is considered to be a conventional approach to comprehensive amplification from low input DNA. The chimeric reads generated in MDA lead to severe disruption in some studies, including those focusing on heterogeneity, structural variation, and genetic recombi...

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Detalles Bibliográficos
Autores principales: Tu, Jing, Lu, Na, Duan, Mengqin, Huang, Mengting, Chen, Liang, Li, Junji, Guo, Jing, Lu, Zuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372508/
https://www.ncbi.nlm.nih.gov/pubmed/28245591
http://dx.doi.org/10.3390/ijms18030492