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Distinct Antigen Delivery Systems Induce Dendritic Cells’ Divergent Transcriptional Response: New Insights from a Comparative and Reproducible Computational Analysis

Vaccination is the most successful and cost-effective method to prevent infectious diseases. However, many vaccine antigens have poor in vivo immunogenic potential and need adjuvants to enhance immune response. The application of systems biology to immunity and vaccinology has yielded crucial insigh...

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Detalles Bibliográficos
Autores principales: Costa, Valerio, Righelli, Dario, Russo, Francesco, De Berardinis, Piergiuseppe, Angelini, Claudia, D’Apice, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372510/
https://www.ncbi.nlm.nih.gov/pubmed/28245601
http://dx.doi.org/10.3390/ijms18030494