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Distinct Antigen Delivery Systems Induce Dendritic Cells’ Divergent Transcriptional Response: New Insights from a Comparative and Reproducible Computational Analysis
Vaccination is the most successful and cost-effective method to prevent infectious diseases. However, many vaccine antigens have poor in vivo immunogenic potential and need adjuvants to enhance immune response. The application of systems biology to immunity and vaccinology has yielded crucial insigh...
Autores principales: | Costa, Valerio, Righelli, Dario, Russo, Francesco, De Berardinis, Piergiuseppe, Angelini, Claudia, D’Apice, Luciana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372510/ https://www.ncbi.nlm.nih.gov/pubmed/28245601 http://dx.doi.org/10.3390/ijms18030494 |
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