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Peroxisome Proliferator-Activated Receptor α Activation Is Not the Main Contributor to Teratogenesis Elicited by Polar Compounds from Oxidized Frying Oil

We previously reported that polar compounds (PO) in cooking oil are teratogenic and perturbed retinoic acid (RA) metabolism. Considering PO as a potent peroxisome proliferator-activated receptor α (PPARα) activator, this study aimed to investigate the role of PPARα in PO-induced teratogenesis and di...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Shun, Lin, Ting-Yi, Wu, Jia-Jiuan, Yao, Hsien-Tsung, Chang, Sunny Li-Yun, Chao, Pei-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372526/
https://www.ncbi.nlm.nih.gov/pubmed/28264465
http://dx.doi.org/10.3390/ijms18030510