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Retinoic Acid Negatively Impacts Proliferation and MC(TC) Specific Attributes of Human Skin Derived Mast Cells, but Reinforces Allergic Stimulability

The Vitamin-A-metabolite retinoic acid (RA) acts as a master regulator of cellular programs. Mast cells (MCs) are primary effector cells of type-I-allergic reactions. We recently uncovered that human cutaneous MCs are enriched with RA network components over other skin cells. Yet, direct experimenta...

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Detalles Bibliográficos
Autores principales: Babina, Magda, Artuc, Metin, Guhl, Sven, Zuberbier, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372541/
https://www.ncbi.nlm.nih.gov/pubmed/28264498
http://dx.doi.org/10.3390/ijms18030525