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RNase L Suppresses Androgen Receptor Signaling, Cell Migration and Matrix Metalloproteinase Activity in Prostate Cancer Cells

The interferon antiviral pathways and prostate cancer genetics converge on a regulated endoribonuclease, RNase L. Positional cloning and linkage studies mapped Hereditary Prostate Cancer 1 (HPC1) to RNASEL. To date, there is no correlation of viral infections with prostate cancer, suggesting that RN...

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Detalles Bibliográficos
Autores principales: Dayal, Shubham, Zhou, Jun, Manivannan, Praveen, Siddiqui, Mohammad Adnan, Ahmad, Omaima Farid, Clark, Matthew, Awadia, Sahezeel, Garcia-Mata, Rafael, Shemshedini, Lirim, Malathi, Krishnamurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372545/
https://www.ncbi.nlm.nih.gov/pubmed/28257035
http://dx.doi.org/10.3390/ijms18030529