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Proline Residues as Switches in Conformational Changes Leading to Amyloid Fibril Formation
Here we discuss studies of the structure, folding, oligomerization and amyloid fibril formation of several proline mutants of human stefin B, which is a protein inhibitor of lysosomal cysteine cathepsins and a member of the cystatin family. The structurally important prolines in stefin B are respons...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372565/ https://www.ncbi.nlm.nih.gov/pubmed/28272335 http://dx.doi.org/10.3390/ijms18030549 |