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Alternative Splicing of hTERT Pre-mRNA: A Potential Strategy for the Regulation of Telomerase Activity

The activation of telomerase is one of the key events in the malignant transition of cells, and the expression of human telomerase reverse transcriptase (hTERT) is indispensable in the process of activating telomerase. The pre-mRNA alternative splicing of hTERT at the post-transcriptional level is o...

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Detalles Bibliográficos
Autores principales: Liu, Xuewen, Wang, Yuchuan, Chang, Guangming, Wang, Feng, Wang, Fei, Geng, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372583/
https://www.ncbi.nlm.nih.gov/pubmed/28272339
http://dx.doi.org/10.3390/ijms18030567