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The Characterization of GSDMB Splicing and Backsplicing Profiles Identifies Novel Isoforms and a Circular RNA That Are Dysregulated in Multiple Sclerosis

Abnormalities in alternative splicing (AS) are emerging as recurrent features in autoimmune diseases (AIDs). In particular, a growing body of evidence suggests the existence of a pathogenic association between a generalized defect in splicing regulatory genes and multiple sclerosis (MS). Moreover, s...

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Detalles Bibliográficos
Autores principales: Cardamone, Giulia, Paraboschi, Elvezia Maria, Rimoldi, Valeria, Duga, Stefano, Soldà, Giulia, Asselta, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372592/
https://www.ncbi.nlm.nih.gov/pubmed/28272342
http://dx.doi.org/10.3390/ijms18030576