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Methyl Gallate Inhibits Osteoclast Formation and Function by Suppressing Akt and Btk-PLCγ2-Ca(2+) Signaling and Prevents Lipopolysaccharide-Induced Bone Loss

In the field of bone research, various natural derivatives have emerged as candidates for osteoporosis treatment by targeting abnormally elevated osteoclastic activity. Methyl gallate, a plant-derived phenolic compound, is known to have numerous pharmacological effects against inflammation, oxidatio...

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Detalles Bibliográficos
Autores principales: Baek, Jong Min, Kim, Ju-Young, Lee, Chang Hoon, Yoon, Kwon-Ha, Lee, Myeung Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372597/
https://www.ncbi.nlm.nih.gov/pubmed/28272351
http://dx.doi.org/10.3390/ijms18030581