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Methyl Gallate Inhibits Osteoclast Formation and Function by Suppressing Akt and Btk-PLCγ2-Ca(2+) Signaling and Prevents Lipopolysaccharide-Induced Bone Loss
In the field of bone research, various natural derivatives have emerged as candidates for osteoporosis treatment by targeting abnormally elevated osteoclastic activity. Methyl gallate, a plant-derived phenolic compound, is known to have numerous pharmacological effects against inflammation, oxidatio...
Autores principales: | Baek, Jong Min, Kim, Ju-Young, Lee, Chang Hoon, Yoon, Kwon-Ha, Lee, Myeung Su |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372597/ https://www.ncbi.nlm.nih.gov/pubmed/28272351 http://dx.doi.org/10.3390/ijms18030581 |
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