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Molecular Basis for Modulation of Metabotropic Glutamate Receptors and Their Drug Actions by Extracellular Ca(2+)

Metabotropic glutamate receptors (mGluRs) associated with the slow phase of the glutamatergic signaling pathway in neurons of the central nervous system have gained importance as drug targets for chronic neurodegenerative diseases. While extracellular Ca(2+) was reported to exhibit direct activation...

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Detalles Bibliográficos
Autores principales: Zou, Juan, Jiang, Jason Y., Yang, Jenny J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372683/
https://www.ncbi.nlm.nih.gov/pubmed/28335551
http://dx.doi.org/10.3390/ijms18030672