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ROS Production and ERK Activity Are Involved in the Effects of d-β-Hydroxybutyrate and Metformin in a Glucose Deficient Condition

Hypoglycemia, a complication of insulin or sulfonylurea therapy in diabetic patients, leads to brain damage. Furthermore, glucose replenishment following hypoglycemic coma induces neuronal cell death. In this study, we investigated the molecular mechanism underlying glucose deficiency-induced cytoto...

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Detalles Bibliográficos
Autores principales: Lamichhane, Santosh, Bastola, Tonking, Pariyar, Ramesh, Lee, Eun-Sol, Lee, Ho-Sub, Lee, Dae Ho, Seo, Jungwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372684/
https://www.ncbi.nlm.nih.gov/pubmed/28335557
http://dx.doi.org/10.3390/ijms18030674