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Sulfur Modifications of the Wobble U(34) in tRNAs and their Intracellular Localization in Eukaryotic Cells

The wobble uridine (U(34)) of transfer RNAs (tRNAs) for two-box codon recognition, i.e., tRNA(Lys)(UUU), tRNA(Glu)(UUC), and tRNA(Gln)(UUG), harbor a sulfur- (thio-) and a methyl-derivative structure at the second and fifth positions of U(34), respectively. Both modifications are necessary to constr...

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Detalles Bibliográficos
Autores principales: Nakai, Yumi, Nakai, Masato, Yano, Takato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372729/
https://www.ncbi.nlm.nih.gov/pubmed/28218716
http://dx.doi.org/10.3390/biom7010017