Dealing with an Unconventional Genetic Code in Mitochondria: The Biogenesis and Pathogenic Defects of the 5-Formylcytosine Modification in Mitochondrial tRNA(Met)

Human mitochondria contain their own genome, which uses an unconventional genetic code. In addition to the standard AUG methionine codon, the single mitochondrial tRNA Methionine (mt-tRNA(Met)) also recognises AUA during translation initiation and elongation. Post-transcriptional modifications of tR...

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Detalles Bibliográficos
Autores principales: Van Haute, Lindsey, Powell, Christopher A., Minczuk, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372736/
https://www.ncbi.nlm.nih.gov/pubmed/28257121
http://dx.doi.org/10.3390/biom7010024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372736/
https://www.ncbi.nlm.nih.gov/pubmed/28257121
http://dx.doi.org/10.3390/biom7010024

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