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Short Communication: Potential Risk of Replication-Competent Virus in HIV-1 Env-Pseudotyped Virus Preparations

Env-pseudotyped viruses are valuable reagents for studies of HIV-1 neutralizing antibodies. It is often assumed that all pseudovirus particles are capable of only a single round of infection, making them a safe alternative to work with live HIV-1. In this study, we show that some Env-pseudotyped vir...

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Detalles Bibliográficos
Autores principales: Bilska, Miroslawa, Tang, Haili, Montefiori, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372769/
https://www.ncbi.nlm.nih.gov/pubmed/27758116
http://dx.doi.org/10.1089/aid.2016.0142