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Fused-Ring Oxazolopyrrolopyridopyrimidine Systems with Gram-Negative Activity

Fused polyheterocyclic derivatives are available by annulation of a tetramate scaffold, and been shown to have antibacterial activity against a Gram-negative, but not a Gram-positive, bacterial strain. While the activity is not potent, these systems are structurally novel showing, in particular, a h...

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Detalles Bibliográficos
Autores principales: Chen, Yiyuan, Moloney, Jonathan G., Christensen, Kirsten E., Moloney, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372982/
https://www.ncbi.nlm.nih.gov/pubmed/28098784
http://dx.doi.org/10.3390/antibiotics6010002