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Bulgecin A: The Key to a Broad-Spectrum Inhibitor That Targets Lytic Transglycosylases

Lytic transglycosylases (Lts) are involved in recycling, cell division, and metabolism of the peptidoglycan. They have been understudied for their usefulness as potential antibacterial targets due to their high redundancy in Gram-negative bacteria. Bulgecin A is an O-sulphonated glycopeptide that ta...

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Detalles Bibliográficos
Autores principales: Williams, Allison H., Wheeler, Richard, Thiriau, Constance, Haouz, Ahmed, Taha, Muhamed-Kheir, Boneca, Ivo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372988/
https://www.ncbi.nlm.nih.gov/pubmed/28241458
http://dx.doi.org/10.3390/antibiotics6010008