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Bulgecin A: The Key to a Broad-Spectrum Inhibitor That Targets Lytic Transglycosylases
Lytic transglycosylases (Lts) are involved in recycling, cell division, and metabolism of the peptidoglycan. They have been understudied for their usefulness as potential antibacterial targets due to their high redundancy in Gram-negative bacteria. Bulgecin A is an O-sulphonated glycopeptide that ta...
Autores principales: | Williams, Allison H., Wheeler, Richard, Thiriau, Constance, Haouz, Ahmed, Taha, Muhamed-Kheir, Boneca, Ivo G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372988/ https://www.ncbi.nlm.nih.gov/pubmed/28241458 http://dx.doi.org/10.3390/antibiotics6010008 |
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