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B-cell tolerance and autoimmunity

Self-reactive B cells are tolerized at various stages of B-cell development and differentiation, including the immature B-cell stage (central tolerance) and the germinal center (GC) B-cell stage, and B-cell tolerance involves various mechanisms such as deletion, anergy, and receptor editing. Self-re...

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Detalles Bibliográficos
Autor principal: Tsubata, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373417/
https://www.ncbi.nlm.nih.gov/pubmed/28408984
http://dx.doi.org/10.12688/f1000research.10583.1