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X chromosome inactivation: new players in the initiation of gene silencing

X chromosome inactivation (XCI) is a dosage compensation process that was adopted by female mammals to balance gene dosage between XX females and XY males. XCI starts with the upregulation of the non-coding RNA Xist, after which most X-linked genes are silenced and acquire a repressive chromatin sta...

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Detalles Bibliográficos
Autores principales: Pinheiro, Ines, Heard, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373419/
https://www.ncbi.nlm.nih.gov/pubmed/28408975
http://dx.doi.org/10.12688/f1000research.10707.1