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When TADs go bad: chromatin structure and nuclear organisation in human disease
Chromatin in the interphase nucleus is organised as a hierarchical series of structural domains, including self-interacting domains called topologically associating domains (TADs). This arrangement is thought to bring enhancers into closer physical proximity with their target genes, which often are...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000Research
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373421/ https://www.ncbi.nlm.nih.gov/pubmed/28408976 http://dx.doi.org/10.12688/f1000research.10792.1 |