Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy

Fasting reduces glucose levels and protects mice against chemotoxicity, yet drugs that promote hyperglycemia are widely used in cancer treatment. Here, we show that dexamethasone (Dexa) and rapamycin (Rapa), commonly administered to cancer patients, elevate glucose and sensitize cardiomyocytes and m...

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Detalles Bibliográficos
Autores principales: Di Biase, Stefano, Shim, Hong Seok, Kim, Kyung Hwa, Vinciguerra, Manlio, Rappa, Francesca, Wei, Min, Brandhorst, Sebastian, Cappello, Francesco, Mirzaei, Hamed, Lee, Changhan, Longo, Valter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373519/
https://www.ncbi.nlm.nih.gov/pubmed/28358805
http://dx.doi.org/10.1371/journal.pbio.2001951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373519/
https://www.ncbi.nlm.nih.gov/pubmed/28358805
http://dx.doi.org/10.1371/journal.pbio.2001951

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