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Amelioration of cognitive impairments in APPswe/PS1dE9 mice is associated with metabolites alteration induced by total salvianolic acid

PURPOSE: Total salvianolic acid (TSA) is extracted from salvia miltiorrhiza; however, to date, there has been limited characterization of its effects on metabolites in Alzheimer’s disease model-APPswe/PS1dE9 mice. The main objective of this study was to investigate the metabolic changes in 7-month-o...

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Detalles Bibliográficos
Autores principales: Shen, Li, Han, Bing, Geng, Yuan, Wang, Jinhua, Wang, Zhengmin, Wang, Mingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373599/
https://www.ncbi.nlm.nih.gov/pubmed/28358909
http://dx.doi.org/10.1371/journal.pone.0174763