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Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability

Kidney podocytes’ function depends on fingerlike projections (foot processes) that interdigitate with those from neighboring cells to form the glomerular filtration barrier. The integrity of the barrier depends on spatial control of dynamics of actin cytoskeleton in the foot processes. We determined...

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Detalles Bibliográficos
Autores principales: Falkenberg, Cibele V., Azeloglu, Evren U., Stothers, Mark, Deerinck, Thomas J., Chen, Yibang, He, John C., Ellisman, Mark H., Hone, James C., Iyengar, Ravi, Loew, Leslie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373631/
https://www.ncbi.nlm.nih.gov/pubmed/28301477
http://dx.doi.org/10.1371/journal.pcbi.1005433