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A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses

Zika virus (ZIKV) is a mosquito borne flavivirus, which was a neglected tropical pathogen until it emerged and spread across the Pacific Area and the Americas, causing large human outbreaks associated with fetal abnormalities and neurological disease in adults. The factors that contributed to the em...

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Detalles Bibliográficos
Autores principales: Tripathi, Shashank, Balasubramaniam, Vinod R. M. T., Brown, Julia A., Mena, Ignacio, Grant, Alesha, Bardina, Susana V., Maringer, Kevin, Schwarz, Megan C., Maestre, Ana M., Sourisseau, Marion, Albrecht, Randy A., Krammer, Florian, Evans, Matthew J., Fernandez-Sesma, Ana, Lim, Jean K., García-Sastre, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373643/
https://www.ncbi.nlm.nih.gov/pubmed/28278235
http://dx.doi.org/10.1371/journal.ppat.1006258