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Protein sorting by lipid phase-like domains supports emergent signaling function in B lymphocyte plasma membranes

Diverse cellular signaling events, including B cell receptor (BCR) activation, are hypothesized to be facilitated by domains enriched in specific plasma membrane lipids and proteins that resemble liquid-ordered phase-separated domains in model membranes. This concept remains controversial and lacks...

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Detalles Bibliográficos
Autores principales: Stone, Matthew B, Shelby, Sarah A, Núñez, Marcos F, Wisser, Kathleen, Veatch, Sarah L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373823/
https://www.ncbi.nlm.nih.gov/pubmed/28145867
http://dx.doi.org/10.7554/eLife.19891