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Effective Combinatorial Immunotherapy for Castration Resistant Prostate Cancer

A significant fraction of advanced prostate cancer (PCa) patients treated with androgen deprivation therapy (ADT) experience relapse with relentless progression to lethal metastatic castration-resistant prostate cancer (mCRPC)(1). Immune checkpoint blockade (ICB) using antibodies against cytotoxic-T...

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Detalles Bibliográficos
Autores principales: Lu, Xin, Horner, James W., Paul, Erin, Shang, Xiaoying, Troncoso, Patricia, Deng, Pingna, Jiang, Shan, Chang, Qing, Spring, Denise J., Sharma, Padmanee, Zebala, John A., Maeda, Dean Y., Wang, Y. Alan, DePinho, Ronald A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374023/
https://www.ncbi.nlm.nih.gov/pubmed/28321130
http://dx.doi.org/10.1038/nature21676