Fludarabine Inhibits K(V)1.3 Currents in Human B Lymphocytes

Fludarabine (F-ara-A) is a purine analog commonly used in the treatment of indolent B cell malignancies that interferes with different aspects of DNA and RNA synthesis. K(V)1.3 K(+) channels are membrane proteins involved in the maintenance of K(+) homeostasis and the resting potential of the cell,...

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Detalles Bibliográficos
Autores principales: de la Cruz, Alicia, Vera-Zambrano, Alba, Peraza, Diego A., Valenzuela, Carmen, Zapata, Juan M., Perez-Chacon, Gema, Gonzalez, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374215/
https://www.ncbi.nlm.nih.gov/pubmed/28408885
http://dx.doi.org/10.3389/fphar.2017.00177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374215/
https://www.ncbi.nlm.nih.gov/pubmed/28408885
http://dx.doi.org/10.3389/fphar.2017.00177

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